Computer-Based De Novo Designs of Tripeptides as Novel Neuraminidase Inhibitors
نویسندگان
چکیده
منابع مشابه
Computer-Based De Novo Designs of Tripeptides as Novel Neuraminidase Inhibitors
The latest influenza A (H1N1) pandemic attracted worldwide attention and called for the urgent development of novel antiviral drugs. Here, seven tripeptides are designed and explored as neuraminidase (NA) inhibitors on the structural basis of known inhibitors. Their interactions with NA are studied and compared with each other, using flexible docking and molecular dynamics simulations. The vari...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2010
ISSN: 1422-0067
DOI: 10.3390/ijms11124932